elvitegravir/cobicistat/emtricitabine/tenofovir DF improves amounts of salmeterol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.Coadministration of encorafenib with sensitive CYP3A4 substrates could bring about elevated toxicity or decreased efficacy of those agents.Watch Closely (one)mitotane decreases amounts of salmeterol by impacting
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